Central Catholic High School has a variety of co-curricular activities for students both in the upper grades as well as the students in junior high. Students are encouraged to take part in clubs and activities as a way to enhance their overall high school and junior high experience. Many of the clubs at Central Catholic offer opportunities for students to perform acts service to the community and school, which is an integral part of the school's mission to "provide service to others".

Each club has its own membership requirements, rules and by-laws. Some clubs are part of a larger national orgnization, such as National Honor Society, Beta, 4-H, and Key Club. Others are school-created clubs, such as A.R.K. and Retreat Team and Drama Club.

Students should consult with each respective club's moderator and or club officers for information on membership.